Clinical Trial Supply Management
End-to-end supply oversight that keeps every patient visit supplied and every study audit-ready.
Bensen Solutions manages clinical supply across Phase I–IV trials for small molecules, biologics, and cell & gene therapies. We own the supply chain from protocol assumptions through final reconciliation, so sponsors and study teams can focus on the science rather than firefighting stockouts.
Our work spans IRT/IXRS strategy, comparator and ancillary sourcing, depot networks, and expiry management — coordinated as a single plan rather than a set of disconnected vendors.
What this engagement includes
Supply planning & simulation
Patient-level demand modeling and Monte Carlo simulation to size production, depots, and safety stock under enrollment uncertainty.
IRT / IXRS strategy
Randomization and trial supply management system design, resupply triggers, and buffer settings that minimize waste without risking site stockouts.
Packaging & labeling oversight
Clinical and commercial packaging design, booklet labels for multi-country studies, and CMO oversight from setup through release.
Comparator & ancillary sourcing
Sourcing of comparator drug, co-medications, and ancillary supplies, including documentation and global logistics.
Depot & distribution network
Global depot selection, import/export and customs coordination, and temperature-controlled distribution to sites.
Expiry & resupply management
Shelf-life tracking, re-labeling and expiry-extension campaigns, and resupply runs that keep product available without overage.
How we work
- 1
Assess protocol & demand
We translate the protocol, enrollment plan, and country mix into a quantified demand and risk picture.
- 2
Design the supply strategy
We define production, packaging, depot, and IRT strategy with the buffers and contingencies the study actually needs.
- 3
Execute & monitor
We run the plan with the CMO, depots, and couriers, tracking inventory, excursions, and resupply in real time.
- 4
Optimize & close out
We tune buffers as data comes in, then handle returns, reconciliation, and destruction at study close.
What you can expect
- No patient visit missed for lack of supply
- Lower overage and drug waste through tuned buffers
- Audit-ready documentation and full chain-of-custody
- One accountable owner across CMOs, depots, and couriers
Frequently asked questions
- What does a clinical supply chain manager do?
- A clinical supply chain manager plans and runs the flow of investigational product through a trial — forecasting demand, overseeing packaging and labeling, setting IRT resupply rules, managing depots and couriers, and ensuring every site has the right kits in date and at temperature, all under GxP compliance.
- How do you prevent drug stockouts at clinical sites?
- Stockouts are prevented with demand simulation, appropriately sized safety stock and IRT resupply triggers, multiple depots for redundancy, and active monitoring of inventory and enrollment so resupply happens before a site runs low rather than after.
- Which trial phases and modalities do you support?
- We support Phase I through Phase IV studies across small molecules, biologics, and cell & gene therapies, including temperature-sensitive and short-shelf-life products that need cold-chain and just-in-time handling.
- What is an IRT/IXRS and why does it matter for supply?
- An IRT (Interactive Response Technology), also called IXRS, is the system that randomizes patients and manages trial inventory. Its resupply triggers and buffer settings directly determine how much drug sits at each site — so getting them right is central to avoiding both stockouts and waste.